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Trifluoperazine[326] H. W. Yang, D. Romo, Tetrahedron Lett. 1998, 39, 2877 H. W. Yang, D. Romo, Tetrahedron 1999, 55, 6403 H. W. Yang, D. Romo, Tetrahedron 1999, 55, 9347. [327] T. A. Engler, M. A. Letavic, J. P. Reddy, J. Am. Chem. Soc. 1991, 113, 5068 [328] T. A. Engler, M. A. Letavic, R. Iyengar, K. O. LaTessa, J. P. Reddy, J. Org. Chem. 1999, 64, 2391 [329] C. Cativiela, P. Lopez, J. A. Mayoral, Tetrahedron: Asymmetry 1991, 2, 1295 [330] G. H. Posner, J. C. Carry, J. K. Lee, D. S. Bull, H. Dai, Tetrahedron Lett. 1994, 35, 1321 [331] H. Kusama, T. Mori, I. Mitani, H. Kashima, I. Kuwajima, Tetrahedron Lett. 1997, 38, 4129 [332] G. Quinkert, M. Del Grosso, A. Bucher, M. Bauch, W. Dring, J. W. Bats, G. Drner, Tetrahedron Lett. 1992, 33, 3617 [333] Progress in the Diels Alder Reaction Means Progress in Steroid Synthesis: G. Quinkert, M. Del Grosso in Stereoselective Synthesis Eds.: E. Ottow, K. Schllkopf, B. G. Schulz ; , Springer, Berlin, 1993, pp. 109 134. [334] G. Quinkert, M. Del Grosso, A. Dring, W. Dring, R. I. Schenkel, M. Bauch, G. T. Dambacher, J. W. Bats, G. Zimmermann, G. Drner, Helv. Chim. Acta 1995, 78, 1345 [335] T. A. Engler, M. A. Letavic, F. Takusagawa, Tetrahedron Lett. 1992, 33, 6731 [336] T. A. Engler, M. A. Letavic, K. O. Lynch, Jr., F. Takusagawa, J. Org. Chem. 1994, 59, 1179 , [337] H. Bienayme Angew. Chem. 1997, 109, 2785 Angew. Chem. Int. Ed. Engl. 1997, 36, 2670 [338] Lobucavir: C. Ireland, P. A. Leeson, J. Castaner, Drugs Future 1997, 22, 359 [339] In other cases, use of the C1-symmetric TADDOL 1 b provided no advantages relative to the original TADDOL 1 a.[326] [340] Either the crotonoyloxazolidinone or the nitrone might be the electrophile, where complexation of the nitrone through the X2TiTADDOLate Lewis acid might also be worth consideration. For a frontal-orbital treatment, see ref. [308, 309, 341]. [341] K. V. Gothelf, K. A. Jrgensen, Acta Chem. Scand. 1996, 50, 652 [342] E. J. Corey, X. M. Cheng, The Logic of Chemical Synthesis, Wiley, New York, 1989. [343] R. W. Baker, G. K. Thomas, S. O. Rea, M. V. Sargent, Aust. J. Chem. 1997, 50, 1151 [344] T. Kanger, K. Kriis, A. Paju, T. Pehk, M. Lopp, Tetrahedron: Asymmetry 1998, 9, 4475 [345] S. Bruns, G. Haufe, Tetrahedron: Asymmetry 1999, 10, 1563 [346] F. Bertozzi, P. Crotti, F. Macchia, M. Pineschi, A. Arnold, B. L. Feringa, Tetrahedron Lett. 1999, 40, 4893 [347] A. Alexakis, C. Benham, X. Fournioux, A. van den Heuvel, J.-M. Leveque, S. March, S. Rosset, Synlett 1999, 1811 1813. [348] E. A. Kretzschmar, J. Kipke, J. Sundermeyer, J. Chem. Soc. Chem. Commun. 1999, 2381 2382. [349] R. Hilgraf, A. Pfaltz, Synlett 1999, 1814 1816. [350] E. Keller, J. Maurer, R. Naasz, T. Schader, A. Meetsma, B. L. Feringa, Tetrahedron: Asymmetry 1998, 9, 2409 [351] D. Seebach, G. Jaeschke, A. Pichota, L. Audergon, Helv. Chim. Acta 1997, 80, 2515 [352] D. H. McConville, J. R. Wolf, R. R. Schrock, J. Am. Chem. Soc. 1993, 115, 4413 [353] For a review of the use of organocerium compounds in organic synthesis covering the literature through 1993 ; and for a recent paper with relevant references, see: Organocerium Compounds in Synthesis: H. J. Liu, K. S. Shia, X. Shang, B. Y. Zhu, Tetrahedron 1999, 55, 3803 Z. Xiao, J. W. Timberlake, Tetrahedron 1998, 54, 4211 [354] K. Sugimoto, S. Aoyagi, C. Kibayashi, J. Org. Chem. 1997, 62, 2322 [355] N. Greeves, J. E. Pease, M. C. Bowden, S. M. Brown, Tetrahedron Lett. 1996, 37, 2675 [356] N. Greeves, J. E. Pease, Tetrahedron Lett. 1996, 37, 5821 [357] P. Mller, P. Nury, Org. Lett. 1999, 1, 439. Buy cheap trifluoperazine onlineCA. Fish were maintained at 16 "C for 3-4 days prior to sacrifice; electric organs were excised and stored at -70 "C prior to use. Bovine brain CaM was prepared by the method either of Watterson et al. 20 ; or of Grand etal. 21 ; . CaM-Sepharose 4B was prepared as described by Klee and Krinks 22 ; . SynapsinI Protein I ; was purified from bovine brain by a modification of the method of Ueda and Intracellular calcium plays an important role in the regu- Greengard 23 ; .This Synapsin I preparation andhistone f3 were gifts lation of several phenomena, such as exocytosis, excitation- of Dr. L. J. DeGennaro of this laboratory. AChR was purified by the contraction coupling, and glycogen metabolism. Many of the method of Lindstrom et al. Method 3, Ref. 24 ; and was the gift of Dr. A. Dalziel Department Yale University ; . Rabbit intracellular actions of Ca2 + are mediated by Caz + -binding polyclonal AChR antibodies of Chemistry, Dr. A. Karlin Columbia were gifts of proteins, of which CaM' appears to be the most widespread University ; . [-y-32P]ATPwas prepared by the method of Glynn and in animalcells 1 ; .Upon interaction withCa2 + , CaM binds to Chappell 25 ; . [Y-~'P]GTP from New England Nuclear. Catalytic was subunit of cyclic AMP-dependent protein kinase from bovine heart, target enzymes and other proteins causing alterations in their a rabbit skeletal muscle myosin light chain fraction, and G-substrate from rabbit cerebellum were kindly provided by Dr. A. C. Nairn of * This work was supported by United States Public Health Service this laboratory. Grants MH-17387 and NS-08440 and a grant from the McKnight Otherreagents and enzymes were obtained from the following Foundation. The costs of publication of this article were defrayed in commercial sources: phosphocellulose paper and DE52 Whatman part by the payment of page charges. This article must therefore be casein, phosvitin, phosphorylase b, histone fzb, ATP, GTP, O-phoshereby marked "advertisement" in accordance with 18 U.S.C. Section phoserine and 0-phosphothreonine Sigma trifluoperazine SmithKline '"I-Protein A Amersham controlled-pore glass, CPG-3000, 1734 solely to indicate this fact. $ Present address, Department of Pharmacological and Physiolog- 120-300 mesh Electro-Nucleonics and Staphylococcus aureus V8 ical Sciences, University of Chicago, 947 East 58th Street, Chicago, protease Miles ; . Synapsin Z Kinase Assays-Two types of assay were employed. For IL 60637. ' The abbreviations used are: CaM, calmodulin; EGTA, ethylene routine rapid screening of column fractions, an assay method based glycol bis j"aminoethy1 ether ; -N, N, N', N'-tetraacetic acid; AChR, on that of Witt and Roskoski 26 ; was used, with Synapsin I as acetylcholine receptor; C, catalytic subunit of CAMP-dependent pro- substrate rather than histone. Assay mixtures contained in 100 p1 of tein kinase; SDS, sodium dodecyl sulfate; Hepes, 4- 2-hydroxyethyl ; - final volume ; : 50 mM Tris-HC1 pH 7.3 ; , 2 m MgClz, 1 mM EGTA M 1-piperazineethanesulfonic acid. or 0.5 mM CaCL plus 100 pg ml of CaM, Synapsin I 3-10 fig ; , and. Dr. McCann treats a patient with pulse-light therapy, a nonablative skin resurfacing technique for the treatment of acne rosacea skin redness. Effect of Baby Friendly on breastfeeding rates at 7 days postpartum Chance of being breastfeed depending upon place of birth 7 days Odds ratio Babies born in a hospital with the UK Baby Friendly Hospital Initiative standard award were 28% P 0.001 ; more likely to be exclusively breastfed at 7 days of postnatal age than those born in other maternity units. From 1995 breastfeeding rates increased significantly faster in hopsitals with Baby Friendly status by 2002: 11.39% v 7.97%. Unknown The authors conclude that being born in a hospital that held the Baby Friendly award increased the chance of being brfeastfed in Scottish infants. + Results are b maternal report which has inherent biases. Ca' + -dependent regulator protein added to the 50-~1 phosphorylation reaction. Maximal stimulation occurs with 4 pg ml and half-maximal requires about 1 pg ml. Stimulation of this synthase kinase by Ca2 + -dependent regulator is blocked by addition of either EGTA 1 mM ; or trifluoperazine 0.1 mM ; Fig. 2 ; . The inhibition by EGTA does not depend on the order of addition of reactants. For example, if synthase-containing CDR-dependent kinase is preincubated with the CDR plus Ca2 + before addition of EGTA and [Y-~~P]ATP, the reaction is blocked by the EGTA not shown ; . Thus, the Ca2'. CDR effect is not due to a protease activation of a kinase. Phosphorylation of synthase at pH 6.8 by CAMPdependent protein kinase catalytic subunit or our preparation of CAMP-independent synthase kinase 3 ; is not significantly affected by 1 mM EGTA or 0.1 mM trifluoperazine results not shown ; . The synthase preparation after heating at 90C for 5 min does not contain CDR as assayed by activation of phosphodiesterase 18 ; . The assay can detect 2 ng of CDR 0.2 mg of synthase. Glycogen ar-synthase can also be phosphorylated and converted to bd-synthase in a reaction catalyzed by the catalytic subunit of CAMP-dependent protein kinase. In this study, synthase phosphorylation catalyzed by several different concentrations of catalytic subunit of CAMP-dependent protein kinase was investigated. For these studies, a., -synthase preparations which contained no detectable kinase activity were used. No stimulatory effect of Ca2 + -dependent regulator protein was detected results not shown and trihexyphenidyl. The models of bundling as a vehicle for price discrimination are typically based on the assumptions that the seller is a monopolist and that demand can be characterized as a statistical distribution of reservation values.26 Given this assumption, bundling can serve two purposes. First, particularly if reservation values are negatively correlated but even if they are not "too" positively correlated, the variation in the sum of the reservation values for the underlying components is lower than the variation in the reservation values for the individual components.27 This "flattening out" of the demand curve can make it possible for a monopolist to extract a greater fraction of the potential surplus than it could with simple pricing.28 Second, mixed bundling gives the monopolist an additional degree of pricing freedom to try to segment markets.29 These models posit a seller with market power over all the potential components of the bundle. That assumption does not match the broad facts of the case.30 First of all, the bundle discount applies to store brands as well as to branded products. Yet, store brands do not have any appreciable market power in the sale of pharmaceuticals. Second, while branding is an important feature of this industry, no single company controls all the brands involved. Even if Johnson & Johnson, which owns the brand Tylenol, has market power in the sale of acetaminophen, it does not have market power in the sale of.
Browse mitochondria articles via key phrases: cyclosporin , trifluoperazine , pore , pore opening , ca2 , surface potential , tert-butyl hydroperoxide , mitochondrial permeability , free fatty acid , long-lasting , cell injury , synergism , delays pore opening , factor , inorganic phosphate , limits pore , bovine serum albumin , n-ethylmaleimide , potential favors , solute-selective , opened , pore regulation , responds , voltage-sensing , effectors , membrane surface potential favors pore opening , cyclosporin-inhibited mitochondria , long-chain alcohols , action , inhibitor , phospholipase , perspective , synergistically , transient , agents , concentration-dependent , i50 , structure , alkanes , free fatty acids , fatty acids , exogenous fatty acids , 2 nmol mg , endogenous , cyclosporin a-treated mitochondria , related mitochondria articles: inhibition of the mitochondrial permeability transition by cyclosporin a during long time 1995 ; biochemistry inhibition by cyclosporin a of a ca2 + -dependent pore in heart mitochondria activated by in 1988 ; biochem j modulation by substrates of the protective effect of cyclosporin a on mitochondrial damage 2002 ; life sci induction of the non-selective mitochondrial pore in lymphoid cells. POSITION AVAILABLE for a full-time, Board Eligible Certified Psychiatrist in well established Psychiatric facility. Indiana license required. JCAH Accredited. Cornpensation including fringes from , 0000, 000. Please send resume and copy of license license renewal to: Personnel Office, Otis Harrison R. Bowen Center, Street, Box 497, Inc. , 850 Warsaw, N. IN and trizivir. Banks will trifluoperazine during your geographical area, you level of trifluoperazine. Input PDK the program generates 24 21 + abdarpa and also parsed constituents with details. 3.1 Procedural Details On running the `nomor ', the program will ask for an input, a nominal base PDK ; , and flash a set of Roman symbols at the right-hand corner of the screen to handle the input-output mechanism in Roman as well in case, facilities for devanagari does not exist ; . On pressing `Enter', the script program will first convert the input into its Ngari equivalent and search in a program specific database to return other required information like the category gender. In case of a nominal base being used in all the three genders, the program, with the help of a small menu will ask the user to enter the gender for which he she would like to see the subanta paradigm. In case, the input nominal base is not found in the database of PDKs, the program will query about the category and the gender s associated with the input through small menus. The information pertinent to the PDK either returned from the database or sought from the user ; , will be fed into the morphological analyzer and thence to the lexicon of case affixes. These two components have the grammar implementation. The morphological analyzer will, first of all, extract the final character string of the nominal base with the help of user-defined predicates called `last str', and `word tail' which use standard predicates `frontstr' and `str len'. The terminating string can be either a vowel represented by its mtr, a consonant represented by its marker called `halanta', a consonant cluster, a conveniently isolated part of the input string or the whole string itself. The clause section of the program has specifications for vowel - mtr, consonants, and other specific constituents as final strings of the nominal base. The program will search for the terminating strings whole words among the clauses section and return the change s if any ; in the nominal base before affixation. In case, program does not find any clause for the said final string whole word, the last clause that is the general rule ; will bound the variables with values. In the next stage, the program will go to the lexicon of case affixes and look for a possible match among various clauses. For each category of the terminating string character, there would be a set of case affixes with their appropriate reduced forms, descriptive details and rules etc. Otherwise, a general set of affixes and other values will return the outputs and troleandomycin. Photo 16. Ankle pressure measurement of the arteria dorsalis pedis Photo: Annika Nordstrm ; The procedure should then be repeated for the arteria tibialis posterior behind below the medial malleolus ; see Photos 17, 18 ; . When the individual arteries have been localised, and a good, clear signal has been obtained, the cuff should be pumped up until the pulsations completely disappear. The pressure should then be slowly released and, when you start hearing the pulsations again, note the value the blood pressure manometer specifies as the ankle pressure. Use the best value the highest ; of the two ankle pressures that are obtained to calculate the index. Use the frequency of 8 MHz for legs of normal size legs and 5 MHz for overweight patients or patients with oedematous legs. The ultrasound Doppler should preferably have loudspeakers. Fluphenazine Stable po daily dose x 1.2; round to nearest 12.5 mg dose; this dose administered every 2-3 weeks Example: 5 mg po bid 12 mg 12.5 mg q 2 weeks Side Effects Alpha-1: orthostatic hypotension, dizziness, reflex tachycardia Histamine-1: sedation, weight gain Muscarinic: dry mouth, constipation, urinary retention, blurred vision, sinus tachycardia, decreased cognition memory Table 6 Agent H-1 alpha-1 muscarinic EPS Low High High Potency Low Low Mid Mid Mid Potency Mid Mid High Low Low Potency High High Table 7 Sedative effect EPS Anticholinergic Orthostasis Chlorpromazine + + + Fluphenazine + + + Haloperidol + + + Loxapine + + + Perphenazine + + + Thioridazine + + + Trifluoperazine + + + Thiothixene + + + Extrapyramidal Symptoms EPS ; : Acute dystonia Prolonged tonic contraction Types: oculogyric crisis ocular ; , retrocollis back ; , torticollis neck ; , glossospasm tongue ; , laryngeal crisis pharygeal ; Incidence- 2-64% Risk factors- high potency antipsychotic; high dose; young male Onset- usually during first 5 days of therapy or with dosage increase Pathophysiology- Dopamine Acetylcholine TreatmentDiphenhydramine 50 mg IM or benztropine 2 mg IM or lorazepam 1-2 mg IM may repeat dose in 15-30 minutes if no improvement Benztropine 1-2 mg po BID or trihexyphenidyl 1-3 mg tid x 7-14 days Decrease AP dosage or change and trovafloxacin.
Siwy, Z.; Trofi n, L.; Kohli, P.; Baker, L. A.; Trautmann, C. * ; Martin, C. R.: Protein biosensors based on biofunctionalized conical gold nanotubes. Journal of the American Chemical Society 127 14 ; : 5000 5001. DOI: 10.1021 ja043910f Spohr, R. * : Status of ion track technology - Prospects of single tracks. Radiation Measurements 40 2 ; : 191 202. DOI: 10.1016 j.radmeas.2005.03.008 Stahl, S.; Alonso, J.; Djekic, S. * ; Kluge, H.-J. * ; Quint, W. * ; Verdu, J.; Vogel, M.; Werth, G.: Phase-sensitive measurement of trapped particle motions. Journal of physics B, Atomic, molecular and optical physics 38 3 ; : 297 304. DOI: 10.1088 0953-4075 38 Stahl, S.; Galve, F. * ; Alonso, J.; Djekic, S.; Quint, W. * ; Valenzuela, T.; Verdu, J.; Vogel, M.; Werth, G.: A planar Penning trap. The European physical journal: D, Atomic, molecular and optical physics 32 1 ; : 139 146. DOI: 10.1140 epjd e2004-00179-x Surzhykov, A.; Fritzsche, S.; Sepp, W. D.; Sthlker, T. * ; o Orsic Muthig, A. * : Polarization and alignment transfer in heavy hydrogen-like ions following radiative electron capture. Nuclear instruments & methods in physics research, Section B, Beam interactions with materials and atoms 235: 276 279. Surzhykov, A.; Fritzsche, S.; Sthlker, T. * ; Tashenov, o S. * : Application of radiative electron capture for the diagnostics of spin-polarized ion beams at storage rings. Physical review letters 94 20 ; : 203202. DOI: 10.1103 PhysRevLett.94.203202 Tahir, N. A. * ; Adonin, A.; Deutsch, C.; Fortov, V. E.; Grandjouan, N.; Geil, B.; Grayaznov, V.; Hoffmann, D. H. H. * ; Kulish, M.; Lomonosov, I. V.; Mintsev, V.; Ni, P. * ; Nikolaev, D.; Piriz, A. R.; Shilkin, N.; Spiller, P. * ; Shutov, A.; Temporal, M. Ternovoi, V.; Udrea, S.; Varentsov, D.: Studies of heavy ion-induced high-energy density states in matter at the GSI Darmstadt SIS-18 and future FAIR facility. Nuclear instruments & methods in physics research, Section A, Accelerators, spectrometers, detectors and associated equipment 544 1 ; : 16 26. DOI: 10.1016 j.nima.2005.01.178 Tahir, N. A. * ; Deutsch, C.; Fortov, V. E.; Gryaznov, V.; Hoffmann, D. H. H. * ; Kulish, M.; Lomonosov, I. V.; Mintsev, V.; Ni, P.; Nikolaev, D.; Piriz, A. R.; Shilkin, N.; Spiller, P. * ; Shutov, A.; Temporal, M.; Ternovoi, V.; Udrea, S.; Varentsov, D.: Proposal for the study of thermophysical properties of high-energy-density matter using current and future heavy-ion accelerator facilities at GSI Darmstadt. Physical review letters 95 3 ; : 035001. DOI: 10.1103 PhysRevLett.95.035001 Tahir, N. A. * ; Goddard, B.; Kain, V.; Schmidt, R.; Shutov, A.; Lomonosov, I. V.; Piriz, A. R.; Temporal.
Von Wasielewski R, Werner M, Fischer R, et al. Lymphocyte-predominant Hodgkin's disease. An immunohistochemical analysis of 208 reviewed Hodgkin's disease cases from the German Hodgkin Study Group. J Pathol 1997; 150: 793803 Watson P, Wood KM, Lodge A, et al. Monoclonal antibodies recognising CD5, CD10 and CD23 in formalin fixed paraffin embedded tissue: production and assessment of their value in the diagnosis of small B cell lymphoma. Histopathology 2000; 36: 145150 Willemze R, Kerl H, Sterry W, et al. EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organisation for Research and Treatment of Cancer. Blood 1997; 90: 35471 World Health Organisation Classification of Tumours. Pathology and Genetics. Tumours of the Haematopoietic and Lymphoid Tissues. Eds Jaffe ES, Harris NL, Stein H, Vardiman J. IARC Press Lyon France and truvada and trifluoperazine.
CURRIE: John Currie b. 1790 at Parkhouse, Corriecravie, Arran, Scotland, died 9 May 1851 on Heron Island, Durham Parish, Restigouche County, NB: m. 7 Feb 1828 in Kilmory Parish, Arran, Bute, Scotland, Catherine Stewart b. 19 May 1805 at Rosebank, Corriecravie, died 19 Dec 1881 at Tarkio, Atchison County, MO, d o Duncan Stewart and Margaret Currie : came to NB in 1838 and settled on Heron Island: Children: 1 ; Neal Currie b. 28 Oct 1829 in Scotland, died unm. 1907 at Durham Center, Restigouche County, NB: 2 ; Mary Currie b. 10 Jan 1832 at Kilmory, Scotland, died 7 Jun 1897 at River Louison, Durham Parish, Restigouche County: m. 5 Mar 1861 River Louison, NB, Nathaniel McNair b. 11 Nov 1833 at Jacquet River, Durham Parish, NB, d. 12 Feb 1894 at Kenesaw, Adams County, NE, s o Archibald McNair and Isabella McMillan: settled at Jacquet River and had six children: 3 ; Peter Currie born 5 Aug 1833 on Island of Arran, Scotland, d. 9 Jan 1907 at Hopkins, Nodaway County, MO: married 24 Jan 1857 New Mills, Colborne Parish, Restigouche County, Mary Dutch born 12 Feb 1836 on Heron Island, NB, d. 9 Nov 1928 at Tarkio, Atchison County, MO: settled on Heron Island and had ten children: 4 ; Janet Currie born 1836 at Kilmory, Scotland, died 1 Mar 1898 at Durham Center, NB: m. 3 Sep 1857 at Jacquet River, NB, Robert McMillan born 1809 at Auchinchairn, Kilbride, Arran, Bute, Scotland, died 20 May 1893 at Jacquet River, NB, s o John McMillan and Mary Nichol: settled at Jacquet River and had eight children: 5 ; Margaret Currie born 1840 at Kilmory, Scotland, d. 25 Aug 1870 at River Louison: married 18 Apr 1865 at Jacquet River, William McKenzie Barclay b. 1830 in NB, d. 10 Aug 1901 in NB: settled at Jacquet River: four children: 6 ; Donald Currie b. 1841 at Kilmory, d. San Francisco, CA, m. Isabella Kerr born at Bathurst, Gloucester County, NB: had one child: 7 ; John Currie b. 20 Aug 1842 on Island of Arran, Scotland, d. 20 Apr 1914, m. 1871 Isabella Stewart Currie b. 3 Feb 1852 in NB, died 14 May 1934, d o John Currie and Elizabeth Ferguson: this family settled at Tarkio, Atchison County, MO: had four children: 8 ; Archibald Currie born 1844 at Corriecravie, Arran, Scotland, died during American Civil War. Source: MC80 2956 LaVida J. Lyda's Descendants of Duncan Stewart, Scotland, Canada & United States, 123 pages. Mend that pools of blood be prepared to contain known quantities of CsA and metabolites and distributed for analysis as part of these quality-assurance programs. IV. Pharmacokinetlcs. TETANUS TOXOID TUBEX . tetracycline hydrochloride . TETRAMUNE VACCINE VIAL . TETRAMUNE VACCINE VIAL . THEO-24 theophylline anhydrous thioguanine thioridazine hydrochloride . thiothixene . thyroid TICE BCG TILADE . TIMENTIN . timolol maleate . TINDAMAX . tizanidine hydrochloride . TOBRADEX . tobramycin sulfate . TONOCARD . TOPAMAX . TOPROL XL TOPROL XL torsemide TRACLEER . tramadol hydrochloride . trazadone hydrochloride . trazadone hydrochloride . tretinoin triamcinolone 0.1% paste . triamcinolone acetonide . triamterene with hydrochlorothiazide . trifluridine trifluoperazine hydrochloride . trihexyphenidyl . TRIHIBIT VACCINE VIAL . TRIHIBIT VACCINE VIAL tri-immunol vial . tri-immunol vial . TRILEPTAL . trimazide trimethoprim. Structure-activity relationships in a series of substituted indolocarbazoles: Topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties. J Med Chem 39: 4471-4477, 1996 Prade L, Engh RA, Girod A, Kinzel V, Huber R, Bossemeyer D: Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure 5: 16271637, 1997 Prudhomme M: Indolocarbazoles as anti-cancer agents. Curr Pharm Design 3: 265-290, 1997 Prudhomme M, Anizon F, Moreau P: Recent developments in the synthesis of indolocarbazoles, topoisomerase I inhibitors. Rec Res Dev Synth Org Chem 279-106, 1999 Prudhomme M: Recent developments of rebeccamycin analogues as topoisomerase I inhibitors and antitumor agents. Curr Med Chem 7: 1189-1212, 2000 Prudhomme M: Rebeccamycin analogs as anti-cancer agents. Eur J Med Chem 38: 123-140, 2003 Prudhomme M, Marminon C, Routier S, Coudert G, Merour J-Y, Hickman J, Pierre A, Renard P Pfeiffer B: , Preparation of pyrido-pyrido-pyrrolo pyrrolo-indole and pyrido-pyrrolo pyrrolo carbazole nucleoside analogs as antitumor agents. PCT Int. Appl. WO 2003002563, Les Laboratoires Servier, Fr. ; 79 pp., 2003 Prudhomme M: Biological targets of antitumor indolocarbazoles bearing a sugar moiety. Curr Med Chem: Anti-Cancer Agents 4: 509-521, 2004 Prudhomme M, Hugon B, Anizon F, Hickman J, Pierre A, Golsteyn R, Renard P Pfeiffer B: Preparation of , pyrrolo[3, 4-c]carbazoles and pyrido[2, 3-b]pyrrolo[3, 4e]indoles as antitumor agents for treating leukemia. Fr. Demande FrP 2845995, Les Laboratoires Servier, Fr. ; 71 pp., 2004a Prudhomme M, Hugon B, Anizon F, Hickman J, Pierre A, Golsteyn R, Renard P Pfeiffer B: New anticancer bis, fused [3, 4-a: 3, 4-c]carbazole derivatives, process for their preparation, and pharmaceutical compositions containing them. Eur. Pat. Appl. EPO 1411057, Les Laboratoires Servier, Fr. ; 42 pp., 2004b Prudhomme M: Staurosporines and structurally related indolocarbazoles as antitumor agents. Anticancer Agents Nat Prod 499-517, 2005 Regenass U, Caravatti G, Fredenhagen A, Wacker O: Indolocarbazole alkaloid derivatives for sensitizing multidrug-resistant cells to antitumor agents. PCT Int. Appl. WO 9532975, Ciba-Geigy A.-G., Switz. ; 61 pp., 1995 Riley DA, Simpkins NS: Synthesis of novel carbocyclic analogues of indolocarbazole natural products. Tetrahedron Lett 40: 3929-3932, 1999 Routier S, Coudert G, Merour JY: Synthesis of naphthopyrrolo[3, 4-c]carbazoles. Tetrahedron Lett 42: 7025-7028, 2001 Routier S, Coudert G, Merour J-Y, Caignard DH: First synthesis of symmetrical and non-symmetrical azaindolocarbazole derivatives. Tetrahedron Lett 43: 2561-2564, 2002a Routier S, Ayerbe N, Merour J-Y, Coudert G, Bailly C, Pierre A, Pfeiffer B, Caignard D-H, Renard P: Synthesis and biological evaluation of 7-azaindolocarbazoles. Tetrahedron 58: 6621-6630, 2002b Routier S, Peixoto P Merour J-Y, Coudert G, Dias N, Bailly , C, Pierre A, Leonce S, Caignard D-H: Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents. 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